BioBlender: a Software for Intuitive Representation of Surface Properties of Biomolecules

In this and the associated article BioBlender: A Software for Intuitive Representation of Surface Properties of Biomolecules [1], we present BioBlender as a complete instrument for the elaboration of motion (here) and the visualization [1] of proteins and other macromolecules, using instruments of computer graphics. A vast number of protein (if not most) exert their function through some extent of motion. Despite recent advances in higly performant methods, it is very difficult to obtain direct information on conformational changes of molecules. However, several systems exist that can shed some light on the variability of conformations of a single peptide chain; among them, NMR methods provide collections of a number of static 'shots' of a moving protein. Starting from this data, and assuming that if a protein exists in more than 1 conformation it must be able to transit between the different states, we have elaborated a system that makes ample use of the computational power...

• Type: Journal
• Year: 2010
• Where: CORR
• Authors: Raluca Mihaela Andrei, Marco Callieri, Maria Francesca Zini, Tiziana Loni, Giuseppe Maraziti, Mike Chen Pan, Monica Zoppè
• Keywords: Associated Article Bioblender, CORR 2010, Education, Protein, Single Peptide Chain