The shrinking processor feature size, lower threshold voltage and increasing clock frequency make modern processors highly vulnerable to transient faults. Architectural Vulnerability Factor (AVF) reflects the possibility that a transient fault eventually causes a visible error in the program output, and it indicates a system's susceptibility to transient faults. Therefore, the awareness of the AVF especially at early design stage is greatly helpful to achieve a trade-off between system performance and reliability. However, tracking the AVF during program execution is extremely costly, which makes accurate AVF prediction extraordinarily attractive to computer architects. In this paper, we propose to use Boosted Regression Trees, a nonparametric tree-based predictive modeling scheme, to identify the correlation across workloads, execution phases and processor configurations between a key processor structure's AVF and various performance metrics. The proposed method not only ma...