To answer the challenges of globally distributed organizations facing constant transformation of work, means of ICT supported interorganizational knowledge-creation is needed. First, concept of organizational knowledgecreation is studied and further enriched with concepts of practice and object of activity to conceptualize the social and transforming nature of knowledge. Second, Change Laboratory is introduced as a theory based method of implementing local organizational knowledge-creation. An empirical case of Change Laboratory in a global organization network is presented and the envisioned ICT tools to support the transition from local to networked knowledge-creation are introduced.