2DB: a Proteomics database for storage, analysis, presentation, and retrieval of information from mass spectrometric experiments

Background: The amount of information stemming from proteomics experiments involving (multi dimensional) separation techniques, mass spectrometric analysis, and computational analysis is ever-increasing. Data from such an experimental workflow needs to be captured, related and analyzed. Biological experiments within this scope produce heterogenic data ranging from pictures of one or two-dimensional protein maps and spectra recorded by tandem mass spectrometry to text-based identifications made by algorithms which analyze these spectra. Additionally, peptide and corresponding protein information needs to be displayed. Results: In order to handle the large amount of data from computational processing of mass spectrometric experiments, automatic import scripts are available and the necessity for manual the database has been minimized. Information is in a generic format which abstracts from specific software tools typically used in such an experimental workflow. The software is therefore ...

• Type: Journal
• Year: 2008
• Where: BMCBI
• Authors: Jens Allmer, Sebastian Kuhlgert, Michael Hippler
• Keywords: BMCBI 2008, Information, Protein, Protein Maps