BioBuilder as a database development and functional annotation platform for proteins

Background: The explosion in biological information creates the need for databases that are easy to develop, easy to maintain and can be easily manipulated by annotators who are most likely to be biologists. However, deployment of scalable and extensible databases is not an easy task and generally requires substantial expertise in database development. Results: BioBuilder is a Zope-based software tool that was developed to facilitate intuitive creation of protein databases. Protein data can be entered and annotated through web forms along with the flexibility to add customized annotation features to protein entries. A built-in review system permits a global team of scientists to coordinate their annotation efforts. We have already used BioBuilder to develop Human Protein Reference Database http://www.hprd.org, a comprehensive annotated repository of the human proteome. The data can be exported in the extensible markup language (XML) format, which is rapidly becoming as the standard fo...

• Type: Journal
• Year: 2004
• Where: BMCBI
• Authors: J. Daniel Navarro, Naveen Talreja, Suraj Peri, B. M. Vrushabendra, B. P. Rashmi, N. Padma, Vineeth Surendranath, Chandra Kiran Jonnalagadda, P. S. Kousthub, Nandan Deshpande, K. Shanker, Akhilesh Pandey
• Keywords: BMCBI 2004, Database, Protein, Proteomic Data