A web application has been developed using the Microsoft .NET technology, which allows to use the Mathematica software from any personal computer connected to Internet. It is not necessary to have the Mathematica software in the own computer, therefore the requirements are limited to have a web browser. All the power of a high level package for numerical and symbolic calculation can be used with no need to spend great amounts of money in individual licenses. This allows students to use this software from their houses, by means of a simple interface, in any subject or project with mathematical calculations, even to attend virtual laboratories. Key words: e-learning, virtual laboratory, Mathematica, .NET technology.