An open source infrastructure for managing knowledge and finding potential collaborators in a domain-specific subset of PubMed,

Background: Identifying relevant research in an ever-growing body of published literature is becoming increasingly difficult. Establishing domain-specific knowledge bases may be a more effective and efficient way to manage and query information within specific biomedical fields. Adopting controlled vocabulary is a critical step toward data integration and interoperability in any information system. We present an open source infrastructure that provides a powerful capacity for managing and mining data within a domain-specific knowledge base. As a practical application of our infrastructure, we presented two applications – Literature Finder and Investigator Browser – as well as a tool set for automating the data curating process for the human genome published literature database. The design of this infrastructure makes the system potentially extensible to other data sources. Results: Information retrieval and usability tests demonstrated that the system had high rates of recall and ...

• Type: Journal
• Year: 2007
• Where: BMCBI
• Authors: Wei Yu, Ajay Yesupriya, Anja Wulf, Junfeng Qu, Muin J. Khoury, Marta Gwinn
• Keywords: Biomedical Field, BMCBI 2007, Data Integration, Domain-specific Knowledge Base