BMCBI
2010
13 years 10 months ago
2010
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
BMCBI
2008
13 years 11 months ago
2008
Background: Genome-wide association studies (GWAS) aim to identify genetic variants (usually single nucleotide polymorphisms [SNPs]) across the entire human genome that are associ...
BMCBI
2008
13 years 11 months ago
2008
Background: Recent advances in global genomic profiling methodologies have enabled multidimensional characterization of biological systems. Complete analysis of these genomic prof...
BMCBI
2008
13 years 11 months ago
2008
Background: During the most recent decade many Bayesian statistical models and software for answering questions related to the genetic structure underlying population samples have...
BMCBI
2008
13 years 11 months ago
2008
Background: Medium- to large-scale expression profiling using quantitative polymerase chain reaction (qPCR) assays are becoming increasingly important in genomics research. A majo...
BMCBI
2008
13 years 11 months ago
2008
Background: Microsatellite (simple sequence repeat
BMCBI
2010
13 years 11 months ago
2010
BMCBI
2010
13 years 11 months ago
2010
Background: Exon arrays provide a way to measure the expression of different isoforms of genes in an organism. Most of the procedures to deal with these arrays are focused on gene...
BMCBI
2010
13 years 11 months ago
2010
Background: Large microarray datasets have enabled gene regulation to be studied through coexpression analysis. While numerous methods have been developed for identifying differen...
