PLAN: a web platform for automating high-throughput BLAST searches and for managing and mining results

Background: BLAST searches are widely used for sequence alignment. The search results are commonly adopted for various functional and comparative genomics tasks such as annotating unknown sequences, investigating gene models and comparing two sequence sets. Advances in sequencing technologies pose challenges for high-throughput analysis of large-scale sequence data. A number of programs and hardware solutions exist for efficient BLAST searching, but there is a lack of generic software solutions for mining and personalized management of the results. Systematically reviewing the results and identifying information of interest remains tedious and time-consuming. Results: Personal BLAST Navigator (PLAN) is a versatile web platform that helps users to carry out various personalized pre- and post-BLAST tasks, including: (1) query and target sequence database management, (2) automated high-throughput BLAST searching, (3) indexing and searching of results, (4) filtering results online, (5) ma...

• Type: Journal
• Year: 2007
• Where: BMCBI
• Authors: Ji He, Xinbin Dai, Xuechun Zhao
• Keywords: Blast, BLAST Searches, BMCBI 2007, Sequence Alignment