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» A Characterization of Constructive Dimension
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BMCBI
2010
153views more  BMCBI 2010»
13 years 10 months ago
Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...
BMCBI
2008
130views more  BMCBI 2008»
13 years 10 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
BMCBI
2007
105views more  BMCBI 2007»
13 years 10 months ago
Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor sti
Background: High-throughput experiments, such as with DNA microarrays, typically result in hundreds of genes potentially relevant to the process under study, rendering the interpr...
Rob Jelier, Guido Jenster, Lambert C. J. Dorssers,...
CORR
2010
Springer
153views Education» more  CORR 2010»
13 years 10 months ago
To Feed or Not to Feed Back
We study the communication over Finite State Channels (FSCs), where the encoder and the decoder can control the availability or the quality of the noise-free feedback. Specificall...
Himanshu Asnani, Haim H. Permuter, Tsachy Weissman
CSCW
2008
ACM
13 years 10 months ago
Physical and Digital Artifact-Mediated Coordination in Building Design
We conducted an ethnographic field study examining how a building design team used representational artifacts to coordinate the design of building systems, structure, and architect...
Melanie Tory, Sheryl Staub-French, Barry A. Po, Fu...