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BIOINFORMATICS
2010
170views more  BIOINFORMATICS 2010»
13 years 7 months ago
Joint estimation of DNA copy number from multiple platforms
DNA copy number variants (CNV) are gains and losses of segments of chromosomes, and comprise an important class of genetic variation. Recently, various microarray hybridization ba...
Nancy R. Zhang, Yasin Senbabaoglu, Jun Z. Li
BMCBI
2007
101views more  BMCBI 2007»
13 years 7 months ago
Statistical validation of megavariate effects in ASCA
Background: Innovative extensions of (M) ANOVA gain common ground for the analysis of designed metabolomics experiments. ASCA is such a multivariate analysis method; it has succes...
Daniel J. Vis, Johan A. Westerhuis, Age K. Smilde,...
BMCBI
2006
131views more  BMCBI 2006»
13 years 7 months ago
Statistical modeling of biomedical corpora: mining the Caenorhabditis Genetic Center Bibliography for genes related to life span
Background: The statistical modeling of biomedical corpora could yield integrated, coarse-to-fine views of biological phenomena that complement discoveries made from analysis of m...
David M. Blei, K. Franks, Michael I. Jordan, I. Sa...
FGCS
2006
74views more  FGCS 2006»
13 years 7 months ago
A performance model of non-deterministic particle transport on large-scale systems
In this work we present a predictive analytical model that encompasses the performance and scaling characteristics of a nondeterministic particle transport application, MCNP (Mont...
Mark M. Mathis, Darren J. Kerbyson, Adolfy Hoisie
BMCBI
2004
146views more  BMCBI 2004»
13 years 7 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker