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BMCBI
2007
103views more  BMCBI 2007»
13 years 8 months ago
Dynamic simulation of regulatory networks using SQUAD
Background: The ambition of most molecular biologists is the understanding of the intricate network of molecular interactions that control biological systems. As scientists uncove...
Alessandro Di Cara, Abhishek Garg, Giovanni De Mic...
BMCBI
2011
12 years 11 months ago
Acorn: A grid computing system for constraint based modeling and visualization of the genome scale metabolic reaction networks v
Background: Constraint-based approaches facilitate the prediction of cellular metabolic capabilities, based, in turn on predictions of the repertoire of enzymes encoded in the gen...
Jacek Sroka, Lukasz Bieniasz-Krzywiec, Szymon Gwoz...
BIBM
2009
IEEE
151views Bioinformatics» more  BIBM 2009»
14 years 2 months ago
Detection of Gene Orthology Based on Protein-Protein Interaction Networks
Abstract—Ortholog detection methods present a powerful approach for finding genes that participate in similar biological processes across different organisms, extending our unde...
Fadi Towfic, M. Heather West Greenlee, Vasant Hona...
BMCBI
2008
97views more  BMCBI 2008»
13 years 8 months ago
MCM-test: a fuzzy-set-theory-based approach to differential analysis of gene pathways
Background: Gene pathway can be defined as a group of genes that interact with each other to perform some biological processes. Along with the efforts to identify the individual g...
Lily R. Liang, Vinay Mandal, Yi Lu, Deepak Kumar
BMCBI
2008
127views more  BMCBI 2008»
13 years 8 months ago
Gene and pathway identification with Lp penalized Bayesian logistic regression
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...