Background: Direct in vivo investigation of human metabolism is complicated by the distinct metabolic functions of various sub-cellular organelles. Diverse micro-environments in d...
Background: Gene function analysis often requires a complex and laborious sequence of laboratory and computer-based experiments. Choosing an effective experimental design generall...
Oliver Laule, Matthias Hirsch-Hoffmann, Tomas Hruz...
Background: Recent progresses in high-throughput proteomics have provided us with a first chance to characterize protein interaction networks (PINs), but also raised new challenge...
Background: The systematic analysis of protein-protein interactions can enable a better understanding of cellular organization, processes and functions. Functional modules can be ...
Background: With the exponential increase in genomic sequence data there is a need to develop automated approaches to deducing the biological functions of novel sequences with hig...