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» A Gene Network Model for Developing Cell Lineages
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BMCBI
2007
182views more  BMCBI 2007»
13 years 7 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
RECOMB
2005
Springer
14 years 7 months ago
Reconstruction of Reticulate Networks from Gene Trees
Abstract. One of the simplest evolutionary models has molecular sequences evolving from a common ancestor down a bifurcating phylogenetic tree, experiencing point-mutations along t...
Daniel H. Huson, Tobias H. Klöpper, Pete J. L...
CSB
2004
IEEE
131views Bioinformatics» more  CSB 2004»
13 years 11 months ago
Improved Fourier Transform Method for Unsupervised Cell-Cycle Regulated Gene Prediction
Motivation: Cell-cycle regulated gene prediction using microarray time-course measurements of the mRNA expression levels of genes has been used by several researchers. The popular...
Karuturi R. Krishna Murthy, Liu Jian Hua
ICCS
2007
Springer
14 years 1 months ago
A Multiscale, Cell-Based Framework for Modeling Cancer Development
We use a systems approach to develop a predictive model that medical researchers can use to study and treat cancerous tumors. Our multiscale, cell-based model includes intracellula...
Yi Jiang
CMSB
2004
Springer
13 years 11 months ago
Residual Bootstrapping and Median Filtering for Robust Estimation of Gene Networks from Microarray Data
We propose a robust estimation method of gene networks based on microarray gene expression data. It is well-known that microarray data contain a large amount of noise and some outl...
Seiya Imoto, Tomoyuki Higuchi, SunYong Kim, Euna J...