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» A Gene Network Model for Developing Cell Lineages
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BMCBI
2007
182views more  BMCBI 2007»
15 years 3 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
119
Voted
RECOMB
2005
Springer
16 years 3 months ago
Reconstruction of Reticulate Networks from Gene Trees
Abstract. One of the simplest evolutionary models has molecular sequences evolving from a common ancestor down a bifurcating phylogenetic tree, experiencing point-mutations along t...
Daniel H. Huson, Tobias H. Klöpper, Pete J. L...
CSB
2004
IEEE
131views Bioinformatics» more  CSB 2004»
15 years 7 months ago
Improved Fourier Transform Method for Unsupervised Cell-Cycle Regulated Gene Prediction
Motivation: Cell-cycle regulated gene prediction using microarray time-course measurements of the mRNA expression levels of genes has been used by several researchers. The popular...
Karuturi R. Krishna Murthy, Liu Jian Hua
ICCS
2007
Springer
15 years 9 months ago
A Multiscale, Cell-Based Framework for Modeling Cancer Development
We use a systems approach to develop a predictive model that medical researchers can use to study and treat cancerous tumors. Our multiscale, cell-based model includes intracellula...
Yi Jiang
CMSB
2004
Springer
15 years 7 months ago
Residual Bootstrapping and Median Filtering for Robust Estimation of Gene Networks from Microarray Data
We propose a robust estimation method of gene networks based on microarray gene expression data. It is well-known that microarray data contain a large amount of noise and some outl...
Seiya Imoto, Tomoyuki Higuchi, SunYong Kim, Euna J...