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» A Gene Network Model for Developing Cell Lineages
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BMCBI
2010
84views more  BMCBI 2010»
13 years 7 months ago
An integrated analysis of molecular aberrations in NCI-60 cell lines
Background: Cancer is a complex disease where various types of molecular aberrations drive the development and progression of malignancies. Large-scale screenings of multiple type...
Chen-Hsiang Yeang
BMCBI
2006
249views more  BMCBI 2006»
13 years 7 months ago
Gene functional similarity search tool (GFSST)
Background: With the completion of the genome sequences of human, mouse, and other species and the advent of high throughput functional genomic research technologies such as biomi...
Peisen Zhang, Jinghui Zhang, Huitao Sheng, James J...
BMCBI
2006
133views more  BMCBI 2006»
13 years 7 months ago
Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae
Background: Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carri...
Illés J. Farkas, Chuang Wu, Chakra Chennubh...
CSB
2005
IEEE
189views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Learning Yeast Gene Functions from Heterogeneous Sources of Data Using Hybrid Weighted Bayesian Networks
We developed a machine learning system for determining gene functions from heterogeneous sources of data sets using a Weighted Naive Bayesian Network (WNB). The knowledge of gene ...
Xutao Deng, Huimin Geng, Hesham H. Ali
ECAL
2005
Springer
14 years 1 months ago
CelloS: A Multi-level Approach to Evolutionary Dynamics
We study the evolution of simple cells that are equipped with a genome, a rudimentary gene regulation network at transcription level and two classes of functional genes: motion eï¬...
Camille Stephan-Otto Attolini, Peter F. Stadler, C...