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» A Gene Network Model for Developing Cell Lineages
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BMCBI
2004
135views more  BMCBI 2004»
13 years 7 months ago
Information assessment on predicting protein-protein interactions
Background: Identifying protein-protein interactions is fundamental for understanding the molecular machinery of the cell. Proteome-wide studies of protein-protein interactions ar...
Nan Lin, Baolin Wu, Ronald Jansen, Mark Gerstein, ...
ICPP
2009
IEEE
14 years 2 months ago
Speeding Up Distributed MapReduce Applications Using Hardware Accelerators
—In an attempt to increase the performance/cost ratio, large compute clusters are becoming heterogeneous at multiple levels: from asymmetric processors, to different system archi...
Yolanda Becerra, Vicenç Beltran, David Carr...
BMCBI
2007
155views more  BMCBI 2007»
13 years 7 months ago
ProCMD: a database and 3D web resource for protein C mutants
Background: Activated Protein C (ProC) is an anticoagulant plasma serine protease which also plays an important role in controlling inflammation and cell proliferation. Several mu...
Pasqualina D'Ursi, Francesca Marino, Andrea Caprer...
BMCBI
2008
226views more  BMCBI 2008»
13 years 7 months ago
ProteoLens: a visual analytic tool for multi-scale database-driven biological network data mining
Background: New systems biology studies require researchers to understand how interplay among myriads of biomolecular entities is orchestrated in order to achieve high-level cellu...
Tianxiao Huan, Andrey Y. Sivachenko, Scott H. Harr...
RECOMB
2006
Springer
14 years 7 months ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...