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» A Method of Requirement Inconsistency Analysis
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BMCBI
2010
208views more  BMCBI 2010»
15 years 4 months ago
Using machine learning to speed up manual image annotation: application to a 3D imaging protocol for measuring single cell gene
Background: Image analysis is an essential component in many biological experiments that study gene expression, cell cycle progression, and protein localization. A protocol for tr...
Zafer Aydin, John I. Murray, Robert H. Waterston, ...
BMCBI
2007
128views more  BMCBI 2007»
15 years 4 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
BMCBI
2005
124views more  BMCBI 2005»
15 years 4 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
BMCBI
2004
228views more  BMCBI 2004»
15 years 4 months ago
An XML standard for the dissemination of annotated 2D gel electrophoresis data complemented with mass spectrometry results
Background: Many proteomics initiatives require a seamless bioinformatics integration of a range of analytical steps between sample collection and systems modeling immediately ass...
Romesh Stanislaus, Liu Hong Jiang, Martha Swartz, ...
CSUR
1999
159views more  CSUR 1999»
15 years 3 months ago
Hubs, authorities, and communities
The Web can be naturally modeled as a directed graph, consisting of a set of abstract nodes (the pages) joined by directional edges (the hyperlinks). Hyperlinks encode a considerab...
Jon M. Kleinberg