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» A New Similarity Measure among Protein Sequences
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BMCBI
2006
120views more  BMCBI 2006»
13 years 9 months ago
An improved distance measure between the expression profiles linking co-expression and co-regulation in mouse
Background: Many statistical algorithms combine microarray expression data and genome sequence data to identify transcription factor binding motifs in the low eukaryotic genomes. ...
Ryung S. Kim, Hongkai Ji, Wing Hung Wong
BMCBI
2007
166views more  BMCBI 2007»
13 years 9 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
BMCBI
2005
100views more  BMCBI 2005»
13 years 9 months ago
EvDTree: structure-dependent substitution profiles based on decision tree classification of 3D environments
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
Jean-Christophe Gelly, Laurent Chiche, Jér&...
NAR
2000
127views more  NAR 2000»
13 years 9 months ago
The EMBL Nucleotide Sequence Database
The European Molecular Biology Laboratory (EMBL) Nucleotide Sequence Database (http://www.ebi.ac. uk/embl/index.html ) is maintained at the European Bioinformatics Institute (EBI)...
Wendy Baker, Alexandra van den Broek, Evelyn Camon...
GCB
2004
Springer
223views Biometrics» more  GCB 2004»
14 years 28 days ago
PoSSuMsearch: Fast and Sensitive Matching of Position Specific Scoring Matrices using Enhanced Suffix Arrays
: In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs. In this paper, we present a new nonheuristic algorithm, ...
Michael Beckstette, Dirk Strothmann, Robert Homann...