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BMCBI
2006
88views more  BMCBI 2006»
15 years 4 months ago
RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes
Background: RNA-dependent gene silencing is becoming a routine tool used in laboratories worldwide. One of the important remaining hurdles in the selection of the target sequence,...
Jean-François Lucier, Lucien Junior Bergero...
BMCBI
2006
113views more  BMCBI 2006»
15 years 4 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
BMCBI
2006
127views more  BMCBI 2006»
15 years 4 months ago
PathogenMIPer: a tool for the design of molecular inversion probes to detect multiple pathogens
Background: Here we describe PathogenMIPer, a software program for designing molecular inversion probe (MIP) oligonucleotides for use in pathogen identification and detection. The...
Sreedevi Thiyagarajan, Miloslav Karhanek, Michael ...
BMCBI
2007
148views more  BMCBI 2007»
15 years 4 months ago
WeederH: an algorithm for finding conserved regulatory motifs and regions in homologous sequences
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Giulio Pavesi, Federico Zambelli, Graziano Pesole
BMCBI
2007
174views more  BMCBI 2007»
15 years 4 months ago
ESTuber db: an online database for Tuber borchii EST sequences
Background: The ESTuber database (http://www.itb.cnr.it/estuber) includes 3,271 Tuber borchii expressed sequence tags (EST). The dataset consists of 2,389 sequences from an in-hou...
Barbara Lazzari, Andrea Caprera, Cristian Cosentin...