Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Background: Expressed sequence tags (ESTs) are single pass reads from randomly selected cDNA clones. They provide a highly cost-effective method to access and identify expressed g...
John Parkinson, David B. Guiliano, Mark L. Blaxter
We analyze expression matrices to identify a priori interesting sets of genes, e.g., genes that are frequently co-regulated. Such matrices provide expression values for given biol...
Background: The Gene Ontology (GO) Consortium organizes genes into hierarchical categories based on biological process, molecular function and subcellular localization. Tools such...
Barry Zeeberg, Hongfang Liu, Ari B. Kahn, Martin E...
Two of the attractions of search-based software engineering (SBSE) derive from the nature of the fitness functions used to guide the search. These have proved to be highly robust...