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SAC
2008
ACM
13 years 6 months ago
Strangeness-based feature weighting and classification of gene expression profiles
Achieving high classification accuracy is a major challenge in the diagnosis of cancer types based on gene expression profiles. These profiles are notoriously noisy in that a larg...
Haifeng Shao, Bei Yu, Joseph H. Nadeau
RECOMB
2004
Springer
14 years 8 months ago
Predicting Genetic Regulatory Response Using Classification: Yeast Stress Response
We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple orga...
Manuel Middendorf, Anshul Kundaje, Chris Wiggins, ...
BMCBI
2007
129views more  BMCBI 2007»
13 years 7 months ago
Exploring inconsistencies in genome-wide protein function annotations: a machine learning approach
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
Carson M. Andorf, Drena Dobbs, Vasant Honavar
JIB
2006
220views more  JIB 2006»
13 years 7 months ago
An assessment of machine and statistical learning approaches to inferring networks of protein-protein interactions
Protein-protein interactions (PPI) play a key role in many biological systems. Over the past few years, an explosion in availability of functional biological data obtained from hi...
Fiona Browne, Haiying Wang, Huiru Zheng, Francisco...
ECCB
2003
IEEE
14 years 29 days ago
Gene networks inference using dynamic Bayesian networks
This article deals with the identification of gene regulatory networks from experimental data using a statistical machine learning approach. A stochastic model of gene interactio...
Bruno-Edouard Perrin, Liva Ralaivola, Aurél...