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BMCBI
2008
84views more  BMCBI 2008»
13 years 7 months ago
poolHiTS: A Shifted Transversal Design based pooling strategy for high-throughput drug screening
Background: A key goal of drug discovery is to increase the throughput of small molecule screens without sacrificing screening accuracy. High-throughput screening (HTS) in drug di...
Raghunandan M. Kainkaryam, Peter J. Woolf
WSC
2007
13 years 10 months ago
IFAO-SIMO: a spatial-simulation based facility network optimization framework
This paper describes an innovative framework, iFAOSimo, which integrates optimization, simulation and GIS (geographic information system) techniques to handle complex spatial faci...
Ming Xie, Wei Wang, Wen Jun Yin, Jin Dong
APLAS
2007
ACM
13 years 11 months ago
Scalable Simulation of Cellular Signaling Networks
Abstract. Given the combinatorial nature of cellular signalling pathways, where biological agents can bind and modify each other in a large number of ways, concurrent or agent-base...
Vincent Danos, Jérôme Feret, Walter F...
RECOMB
2004
Springer
14 years 7 months ago
The Distribution of Inversion Lengths in Bacteria
The distribution of the lengths of genomic segments inverte during the evolutionary divergence of two species cannot be inferred d rectly from the output of genome rearrangement al...
Adrian Maler, David Sankoff, Elisabeth R. M. Tilli...
BMCBI
2008
141views more  BMCBI 2008»
13 years 7 months ago
The development of PIPA: an integrated and automated pipeline for genome-wide protein function annotation
Background: Automated protein function prediction methods are needed to keep pace with high-throughput sequencing. With the existence of many programs and databases for inferring ...
Chenggang Yu, Nela Zavaljevski, Valmik Desai, Seth...