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BMCBI
2008
128views more  BMCBI 2008»
13 years 7 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
ISBI
2008
IEEE
14 years 8 months ago
FMRI brain activity and underlying hemodynamics estimation in a new Bayesian framework
The emerging functional MRI (Magnetic Resonance Imaging), fMRI, imaging modality was developed to obtain non-invasive information regarding the neural processes behind pre-determi...
David M. Afonso, João M. Sanches, Martin H....
BMCBI
2007
146views more  BMCBI 2007»
13 years 7 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
CCE
2004
13 years 7 months ago
Improving convergence of the stochastic decomposition algorithm by using an efficient sampling technique
This work focuses on the basic stochastic decomposition (SD) algorithm of Higle and Sen [J.L. Higle, S. Sen, Stochastic Decomposition, Kluwer Academic Publishers, 1996] for two-st...
José María Ponce-Ortega, Vicente Ric...
BMCBI
2006
110views more  BMCBI 2006»
13 years 7 months ago
Design of a combinatorial DNA microarray for protein-DNA interaction studies
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
Julian Mintseris, Michael B. Eisen