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BMCBI
2007
145views more  BMCBI 2007»
13 years 6 months ago
Improved benchmarks for computational motif discovery
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...
Geir Kjetil Sandve, Osman Abul, Vegard Walseng, Fi...
BMCBI
2004
88views more  BMCBI 2004»
13 years 6 months ago
PhyME: A probabilistic algorithm for finding motifs in sets of orthologous sequences
Background: This paper addresses the problem of discovering transcription factor binding sites in heterogeneous sequence data, which includes regulatory sequences of one or more g...
Saurabh Sinha, Mathieu Blanchette, Martin Tompa
BIOINFORMATICS
2007
74views more  BIOINFORMATICS 2007»
13 years 6 months ago
Simultaneous alignment and annotation of cis-regulatory regions
Genomic transcriptional processes rely heavily on the combinatorial binding of transcription factors on the upstream regions of genes. Analysis and complete characterization of su...
Abha Singh Bais, Steffen Grossmann, Martin Vingron
RECOMB
2001
Springer
14 years 7 months ago
Algorithms for phylogenetic footprinting
Phylogenetic footprinting is a comparative genomics approach for predicting transcription factor binding sites, where a set of orthologous regulatory regions are compared and short...
Mathieu Blanchette
BMCBI
2006
137views more  BMCBI 2006»
13 years 6 months ago
Bounded search for de novo identification of degenerate cis-regulatory elements
Background: The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential ...
Jonathan M. Carlson, Arijit Chakravarty, Radhika S...