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BMCBI
2007
136views more  BMCBI 2007»
13 years 6 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette
ICANNGA
2007
Springer
149views Algorithms» more  ICANNGA 2007»
14 years 27 days ago
Using Real-Valued Meta Classifiers to Integrate and Contextualize Binding Site Predictions
Currently the best algorithms for transcription factor binding site predictions are severely limited in accuracy. However, a non-linear combination of these algorithms could improv...
Mark Robinson, Offer Sharabi, Yi Sun, Rod Adams, R...
CSB
2003
IEEE
124views Bioinformatics» more  CSB 2003»
14 years 1 days ago
SMASHing regulatory sites in DNA by human
Regulatory sequence elements provide important clues to understanding and predicting gene expression. Although the binding sites for hundreds of transcription factors are known, t...
Mihaela Zavolan, Nicholas D. Socci, Nikolaus Rajew...
RECOMB
2004
Springer
14 years 2 days ago
Application of Kernel Method to Reveal Subtypes of TF Binding Motifs
Transcription factor binding sites often contain several subtypes of sequences that follow not just one but several different patterns. We developed a novel sensitive method based ...
Alexander E. Kel, Yuri Tikunov, Nico Voss, Jü...
BMCBI
2007
149views more  BMCBI 2007»
13 years 6 months ago
Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors
Background: Evolutionary conservation has been used successfully to help identify cis-acting DNA regions that are important in regulating tissue-specific gene expression. Motivate...
Xueping Yu, Jimmy J. Lin, Donald J. Zack, Jiang Qi...