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» A Theoretical Analysis of Gene Selection
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KDD
2002
ACM
119views Data Mining» more  KDD 2002»
14 years 9 months ago
Evaluating classifiers' performance in a constrained environment
In this paper, we focus on methodology of finding a classifier with a minimal cost in presence of additional performance constraints. ROCCH analysis, where accuracy and cost are i...
Anna Olecka
JCB
2006
124views more  JCB 2006»
13 years 9 months ago
The Average Common Substring Approach to Phylogenomic Reconstruction
We describe a novel method for efficient reconstruction of phylogenetic trees, based on sequences of whole genomes or proteomes, whose lengths may greatly vary. The core of our me...
Igor Ulitsky, David Burstein, Tamir Tuller, Benny ...
BMCBI
2005
106views more  BMCBI 2005»
13 years 9 months ago
SIMPROT: Using an empirically determined indel distribution in simulations of protein evolution
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
Andy Pang, Andrew D. Smith, Paulo A. S. Nuin, Elis...
APBC
2004
122views Bioinformatics» more  APBC 2004»
13 years 10 months ago
Evolution of Relative Synonymous Codon Usage in Human Immunodeficiency Virus Type 1
Mutation in HIV-1 is extremely rapid, a consequence of a low-fidelity viral reverse transcription process. The envelope gene has been shown to accumulate substitutions at a rate o...
Peter L. Meintjes, Allen G. Rodrigo
BMCBI
2007
145views more  BMCBI 2007»
13 years 9 months ago
The utility of MAS5 expression summary and detection call algorithms
Background: Used alone, the MAS5.0 algorithm for generating expression summaries has been criticized for high False Positive rates resulting from exaggerated variance at low inten...
Stuart D. Pepper, Emma K. Saunders, Laura E. Edwar...