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» A Toolbox of Level Set Methods
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BMCBI
2006
128views more  BMCBI 2006»
13 years 11 months ago
An interactive tool for visualization of relationships between gene expression profiles
Background: Application of phenetic methods to gene expression analysis proved to be a successful approach. Visualizing the results in a 3-dimentional space may further enhance th...
Peter Ruzanov, Steven J. M. Jones
BMCBI
2006
156views more  BMCBI 2006»
13 years 11 months ago
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
Stephan Waack, Oliver Keller, Roman Asper, Thomas ...
BMCBI
2006
190views more  BMCBI 2006»
13 years 11 months ago
SNPs3D: Candidate gene and SNP selection for association studies
Background: The relationship between disease susceptibility and genetic variation is complex, and many different types of data are relevant. We describe a web resource and databas...
Peng Yue, Eugene Melamud, John Moult
BMCBI
2006
140views more  BMCBI 2006»
13 years 11 months ago
MACSIMS : multiple alignment of complete sequences information management system
Background: In the post-genomic era, systems-level studies are being performed that seek to explain complex biological systems by integrating diverse resources from fields such as...
Julie D. Thompson, Arnaud Muller, Andrew M. Waterh...
BMCBI
2007
113views more  BMCBI 2007»
13 years 11 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu