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JBCB
2008
71views more  JBCB 2008»
13 years 8 months ago
Using Indirect protein-protein Interactions for protein Complex Prediction
Protein complexes are fundamental for understanding principles of cellular organizations. Accurate and fast protein complex prediction from the PPI networks of increasing sizes ca...
Hon Nian Chua, Kang Ning, Wing-Kin Sung, Hon Wai L...
BMCBI
2007
227views more  BMCBI 2007»
13 years 8 months ago
Growing functional modules from a seed protein via integration of protein interaction and gene expression data
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...
BMCBI
2005
127views more  BMCBI 2005»
13 years 7 months ago
Are scale-free networks robust to measurement errors?
Background: Many complex random networks have been found to be scale-free. Existing literature on scale-free networks has rarely considered potential false positive and false nega...
Nan Lin, Hongyu Zhao
BMCBI
2010
109views more  BMCBI 2010»
13 years 8 months ago
Functional characterization and topological modularity of molecular interaction networks
Background: Analyzing interaction networks for functional characterization poses significant challenges arising from the noisy, incomplete, and generic nature of both the interact...
Jayesh Pandey, Mehmet Koyutürk, Ananth Grama
BMCBI
2010
179views more  BMCBI 2010»
13 years 8 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...