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» A cluster validity framework for genome expression data
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BMCBI
2010
131views more  BMCBI 2010»
13 years 7 months ago
Prediction of epigenetically regulated genes in breast cancer cell lines
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
WWW
2006
ACM
14 years 8 months ago
Mining clickthrough data for collaborative web search
This paper is to investigate the group behavior patterns of search activities based on Web search history data, i.e., clickthrough data, to boost search performance. We propose a ...
Jian-Tao Sun, Xuanhui Wang, Dou Shen, Hua-Jun Zeng...
BMCBI
2007
136views more  BMCBI 2007»
13 years 7 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette
DMKD
2003
ACM
96views Data Mining» more  DMKD 2003»
14 years 20 days ago
Using transposition for pattern discovery from microarray data
We analyze expression matrices to identify a priori interesting sets of genes, e.g., genes that are frequently co-regulated. Such matrices provide expression values for given biol...
François Rioult, Jean-François Bouli...
RECOMB
2005
Springer
14 years 7 months ago
An Interaction-Dependent Model for Transcription Factor Binding
Transcriptional regulation is accomplished by several transcription factor proteins that bind to specific DNA elements in the relative vicinity of the gene, and interact with each ...
Li-San Wang, Shane T. Jensen, Sridhar Hannenhalli