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BMCBI
2007
109views more  BMCBI 2007»
13 years 7 months ago
Towards a comprehensive structural coverage of completed genomes: a structural genomics viewpoint
Background: Structural genomics initiatives were established with the aim of solving protein structures on a large-scale. For many initiatives, such as the Protein Structure Initi...
Russell L. Marsden, Tony A. Lewis, Christine A. Or...
BMCBI
2008
143views more  BMCBI 2008»
13 years 7 months ago
Gene identification and protein classification in microbial metagenomic sequence data via incremental clustering
Background: The identification and study of proteins from metagenomic datasets can shed light on the roles and interactions of the source organisms in their communities. However, ...
Shibu Yooseph, Weizhong Li, Granger G. Sutton
BMCBI
2007
113views more  BMCBI 2007»
13 years 7 months ago
PILER-CR: Fast and accurate identification of CRISPR repeats
Background: Sequencing of prokaryotic genomes has recently revealed the presence of CRISPR elements: short, highly conserved repeats separated by unique sequences of similar lengt...
Robert C. Edgar
BIBE
2003
IEEE
133views Bioinformatics» more  BIBE 2003»
14 years 23 days ago
A Computational Pipeline for Protein Structure Prediction and Analysis at Genome Scale
The tertiary (3D) structure of a protein contains the essential information for understanding the biological function of the protein at the molecular and cellular levels. Traditio...
Manesh J. Shah, Sergei Passovets, Dongsup Kim, Kyl...
BMCBI
2006
101views more  BMCBI 2006»
13 years 7 months ago
How repetitive are genomes?
Background: Genome sequences vary strongly in their repetitiveness and the causes for this are still debated. Here we propose a novel measure of genome repetitiveness, the index o...
Bernhard Haubold, Thomas Wiehe