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» A custom FPGA for the simulation of gene regulatory networks
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BMCBI
2008
154views more  BMCBI 2008»
13 years 7 months ago
GeNESiS: gene network evolution simulation software
Background: There has been a lot of interest in recent years focusing on the modeling and simulation of Gene Regulatory Networks (GRNs). However, the evolutionary mechanisms that ...
Anton Kratz, Masaru Tomita, Arun Krishnan
JCB
2006
114views more  JCB 2006»
13 years 7 months ago
A General Modeling Strategy for Gene Regulatory Networks with Stochastic Dynamics
A stochastic genetic toggle switch model that consists of two identical, mutually repressive genes is built using the Gillespie algorithm with time delays as an example of a simpl...
Andre Ribeiro, Rui Zhu, Stuart A. Kauffman
CIBCB
2005
IEEE
14 years 1 months ago
Predicting Single Genes Related to Immune-Relevant Processes
— In this paper we address the problem of predicting gene activities by finding gene regulatory dependencies in experimental DNA microarray data. Only few approaches to infer th...
Christian Spieth, Felix Streichert, Nora Speer, Ch...
GECCO
2008
Springer
179views Optimization» more  GECCO 2008»
13 years 8 months ago
Evolution of discrete gene regulatory models
Gene regulatory networks (GRNs) are complex control systems that govern the interaction of genes, which ultimately control cellular processes at the protein level. GRNs can be ted...
Afshin Esmaeili, Christian Jacob
ICCS
2003
Springer
14 years 20 days ago
Modelling Developmental Regulatory Networks
Abstract. This paper introduces a model for simulating regulatory networks that is capable of reproducing spatial and temporal expression patterns in developmental processes. The m...
Tommy Krul, Jaap A. Kaandorp, Joke G. Blom