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» A duplication growth model of gene expression networks
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NIPS
2004
13 years 9 months ago
Joint Probabilistic Curve Clustering and Alignment
Clustering and prediction of sets of curves is an important problem in many areas of science and engineering. It is often the case that curves tend to be misaligned from each othe...
Scott Gaffney, Padhraic Smyth
BMCBI
2008
122views more  BMCBI 2008»
13 years 7 months ago
Reconstructing networks of pathways via significance analysis of their intersections
Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...
Mirko Francesconi, Daniel Remondini, Nicola Nerett...
APBC
2004
116views Bioinformatics» more  APBC 2004»
13 years 9 months ago
Evolving Genetic Regulatory Networks Using an Artificial Genome
Boolean models of genetic regulatory networks (GRNs) have been shown to exhibit many of the characteristic dynamics of real GRNs, with gene expression patterns settling to point a...
Jennifer Hallinan, Janet Wiles
RECOMB
2004
Springer
14 years 8 months ago
Learning Regulatory Network Models that Represent Regulator States and Roles
Abstract. We present an approach to inferring probabilistic models of generegulatory networks that is intended to provide a more mechanistic representation of transcriptional regul...
Keith Noto, Mark Craven
CSB
2005
IEEE
130views Bioinformatics» more  CSB 2005»
14 years 1 months ago
iSimBioSys: An "In Silico" Discrete Event Simulation Framework for Modeling Biological Systems
The genome projects have provided comprehensive information about the basic building blocks of life. The next challenge is to understand how biological functions emerge from compl...
Samik Ghosh, Preetam Ghosh, Kalyan Basu, Sajal K. ...