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» A factor analysis model for functional genomics
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BMCBI
2011
12 years 11 months ago
To aggregate or not to aggregate high-dimensional classifiers
Background: High-throughput functional genomics technologies generate large amount of data with hundreds or thousands of measurements per sample. The number of sample is usually m...
Cheng-Jian Xu, Huub C. J. Hoefsloot, Age K. Smilde
IPPS
2009
IEEE
14 years 2 months ago
Exploring FPGAs for accelerating the phylogenetic likelihood function
Driven by novel biological wet lab techniques such as pyrosequencing there has been an unprecedented molecular data explosion over the last 2-3 years. The growth of biological seq...
Nikolaos Alachiotis, Euripides Sotiriades, Apostol...
KDD
2004
ACM
237views Data Mining» more  KDD 2004»
14 years 8 months ago
Bayesian Model-Averaging in Unsupervised Learning From Microarray Data
Unsupervised identification of patterns in microarray data has been a productive approach to uncovering relationships between genes and the biological process in which they are in...
Mario Medvedovic, Junhai Guo
BMCBI
2007
130views more  BMCBI 2007»
13 years 8 months ago
Differential analysis for high density tiling microarray data
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...
BMCBI
2005
149views more  BMCBI 2005»
13 years 8 months ago
The PD-(D/E)XK superfamily revisited: identification of new members among proteins involved in DNA metabolism and functional pre
Background: The PD-(D/E)XK nuclease superfamily, initially identified in type II restriction endonucleases and later in many enzymes involved in DNA recombination and repair, is o...
Jan Kosinski, Marcin Feder, Janusz M. Bujnicki