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BMCBI
2010
109views more  BMCBI 2010»
13 years 8 months ago
Structural alphabets derived from attractors in conformational space
Background: The hierarchical and partially redundant nature of protein structures justifies the definition of frequently occurring conformations of short fragments as `states'...
Alessandro Pandini, Arianna Fornili, Jens Kleinjun...
BMCBI
2006
178views more  BMCBI 2006»
13 years 8 months ago
MannDB - A microbial database of automated protein sequence analyses and evidence integration for protein characterization
Background: MannDB was created to meet a need for rapid, comprehensive automated protein sequence analyses to support selection of proteins suitable as targets for driving the dev...
Carol L. Ecale Zhou, Marisa Lam, Jason Smith, Adam...
BIBE
2003
IEEE
116views Bioinformatics» more  BIBE 2003»
14 years 2 months ago
An Assessment of a Metric Space Database Index to Support Sequence Homology
Hierarchical metric-space clustering methods have been commonly used to organize proteomes into taxonomies. Consequently, it is often anticipated that hierarchical clustering can ...
Rui Mao, Weijia Xu, Neha Singh, Daniel P. Miranker
BMCBI
2008
149views more  BMCBI 2008»
13 years 8 months ago
Clustering of cognate proteins among distinct proteomes derived from multiple links to a single seed sequence
Background: Modern proteomes evolved by modification of pre-existing ones. It is extremely important to comparative biology that related proteins be identified as members of the s...
Adriano Barbosa-Silva, Venkata P. Satagopam, Reinh...
BMCBI
2007
114views more  BMCBI 2007»
13 years 8 months ago
False occurrences of functional motifs in protein sequences highlight evolutionary constraints
Background: False occurrences of functional motifs in protein sequences can be considered as random events due solely to the sequence composition of a proteome. Here we use a nume...
Allegra Via, Pier Federico Gherardini, Enrico Ferr...