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» A graphical model for predicting protein molecular function
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BMCBI
2004
138views more  BMCBI 2004»
13 years 7 months ago
Constraint Logic Programming approach to protein structure prediction
Background: The protein structure prediction problem is one of the most challenging problems in biological sciences. Many approaches have been proposed using database information ...
Alessandro Dal Palù, Agostino Dovier, Feder...
BMCBI
2005
118views more  BMCBI 2005»
13 years 7 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz
BMCBI
2007
102views more  BMCBI 2007»
13 years 8 months ago
FlexOracle: predicting flexible hinges by identification of stable domains
Background: Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions i...
Samuel Flores, Mark Gerstein
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
14 years 2 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...
NAR
2007
150views more  NAR 2007»
13 years 7 months ago
CellCircuits: a database of protein network models
CellCircuits (http://www.cellcircuits.org) is an openaccess database of molecular network models, designed to bridge the gap between databases of individual pairwise molecular int...
H. Craig Mak, Mike Daly, Bianca Gruebel, Trey Idek...