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» A graphical model for predicting protein molecular function
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BMCBI
2010
136views more  BMCBI 2010»
13 years 8 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
RECOMB
2003
Springer
14 years 8 months ago
Combining phylogenetic and hidden Markov models in biosequence analysis
A few models have appeared in recent years that consider not only the way substitutions occur through evolutionary history at each site of a genome, but also the way the process c...
Adam C. Siepel, David Haussler
VIS
2007
IEEE
138views Visualization» more  VIS 2007»
14 years 9 months ago
Two Level Approach to Efficient Visualization of Protein Dynamics
Proteins are highly flexible and large amplitude deformations of their structure, also called slow dynamics, are often decisive to their function. We present a two-level rendering ...
Ove Daae Lampe, Ivan Viola, Nathalie Reuter, He...
BMCBI
2008
101views more  BMCBI 2008»
13 years 8 months ago
Reranking candidate gene models with cross-species comparison for improved gene prediction
Background: Most gene finders score candidate gene models with state-based methods, typically HMMs, by combining local properties (coding potential, splice donor and acceptor patt...
Qian Liu, Koby Crammer, Fernando C. N. Pereira, Da...
BMCBI
2010
139views more  BMCBI 2010»
13 years 8 months ago
TOPSAN: a collaborative annotation environment for structural genomics
Background: Many protein structures determined in high-throughput structural genomics centers, despite their significant novelty and importance, are available only as PDB depositi...
Dana Weekes, S. Sri Krishna, Constantina Bakolitsa...