Computer modeling and simulation are indispensable for understanding the functioning of an organism on a molecular level. We present an implemented method for the qualitative simu...
Background: Correlations between polymorphic markers and observed phenotypes provide the basis for mapping traits in quantitative genetics. When the phenotype is gene expression, ...
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Hybrid algorithms that combine genetic algorithms with the Nelder-Mead simplex algorithm have been effective in solving certain optimization problems. In this article, we apply a s...
Praveen Koduru, Sanjoy Das, Stephen Welch, Judith ...
Abstract. This paper considers piecewise affine models of genetic regulatory networks and focuses on the problem of detecting switches among different modes of operation in gene e...