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BMCBI
2007
86views more  BMCBI 2007»
13 years 7 months ago
Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
William O. Ward, Carol D. Swartz, Steffen Porwolli...
ISPD
1999
ACM
97views Hardware» more  ISPD 1999»
13 years 11 months ago
A methodology to analyze power, voltage drop and their effects on clock skew/delay in early stages of design
This paper presents a methodology to analyze signal integrity such as power voltage drop and clock skew in early stages of design, more specifically, when RTL-design and early flo...
Masato Iwabuchi, Noboru Sakamoto, Yasushi Sekine, ...
CDC
2009
IEEE
133views Control Systems» more  CDC 2009»
14 years 6 days ago
Kinetic perturbations as robustness analysis tool for biochemical reaction networks
— Models of biochemical reaction networks can be decomposed into a stoichiometric part and a kinetic part. The stoichiometric part describes the structural mass flows while the ...
Steffen Waldherr, Frank Allgöwer, Elling W. J...
BMCBI
2010
150views more  BMCBI 2010»
13 years 7 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
BMCBI
2006
117views more  BMCBI 2006»
13 years 7 months ago
SigFlux: A novel network feature to evaluate the importance of proteins in signal transduction networks
Background: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology sy...
Wei Liu, Dong Li, Jiyang Zhang, Yunping Zhu, Fuchu...