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BMCBI
2010
151views more  BMCBI 2010»
13 years 7 months ago
Misty Mountain clustering: application to fast unsupervised flow cytometry gating
Background: There are many important clustering questions in computational biology for which no satisfactory method exists. Automated clustering algorithms, when applied to large,...
István P. Sugár, Stuart C. Sealfon
COLT
2008
Springer
13 years 9 months ago
Adapting to a Changing Environment: the Brownian Restless Bandits
In the multi-armed bandit (MAB) problem there are k distributions associated with the rewards of playing each of k strategies (slot machine arms). The reward distributions are ini...
Aleksandrs Slivkins, Eli Upfal
ALMOB
2006
106views more  ALMOB 2006»
13 years 7 months ago
Multiple sequence alignment with user-defined anchor points
Background: Automated software tools for multiple alignment often fail to produce biologically meaningful results. In such situations, expert knowledge can help to improve the qua...
Burkhard Morgenstern, Sonja J. Prohaska, Dirk P&ou...
BMCBI
2007
133views more  BMCBI 2007»
13 years 7 months ago
Semi-supervised learning for the identification of syn-expressed genes from fused microarray and in situ image data
Background: Gene expression measurements during the development of the fly Drosophila melanogaster are routinely used to find functional modules of temporally co-expressed genes. ...
Ivan G. Costa, Roland Krause, Lennart Opitz, Alexa...
ICCAD
1997
IEEE
108views Hardware» more  ICCAD 1997»
13 years 11 months ago
Negative thinking by incremental problem solving: application to unate covering
We introduce a new technique to solve exactly a discrete optimization problem, based on the paradigm of “negative” thinking. The motivation is that when searching the space of...
Evguenii I. Goldberg, Luca P. Carloni, Tiziano Vil...