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RECOMB
2006
Springer
14 years 7 months ago
Integrated Protein Interaction Networks for 11 Microbes
We have combined four different types of functional genomic data to create high coverage protein interaction networks for 11 microbes. Our integration algorithm naturally handles s...
Balaji S. Srinivasan, Antal F. Novak, Jason Flanni...
BMCBI
2008
83views more  BMCBI 2008»
13 years 7 months ago
Prioritization of gene regulatory interactions from large-scale modules in yeast
Background: The identification of groups of co-regulated genes and their transcription factors, called transcriptional modules, has been a focus of many studies about biological s...
Ho-Joon Lee, Thomas Manke, Ricardo Bringas, Martin...
GCB
1998
Springer
78views Biometrics» more  GCB 1998»
13 years 11 months ago
Computational approaches to identify Leucine Zippers
The leucine zipper is a dimerization domain occurring mostly in regulatory and thus in many oncogenic proteins. The leucine repeat in the sequence has been traditionally used for ...
Erich Bornberg-Bauer
RECOMB
2005
Springer
14 years 7 months ago
Learning Interpretable SVMs for Biological Sequence Classification
Background: Support Vector Machines (SVMs) ? using a variety of string kernels ? have been successfully applied to biological sequence classification problems. While SVMs achieve ...
Christin Schäfer, Gunnar Rätsch, Sö...
BMCBI
2010
160views more  BMCBI 2010»
13 years 7 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian