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BMCBI
2007
180views more  BMCBI 2007»
13 years 7 months ago
Splicy: a web-based tool for the prediction of possible alternative splicing events from Affymetrix probeset data
Background: The Affymetrix™ technology is nowadays a well-established method for the analysis of gene expression profiles in cancer research studies. However, changes in gene ex...
Davide Rambaldi, Barbara Felice, Viviane Praz, Phi...
BMCBI
2006
181views more  BMCBI 2006»
13 years 7 months ago
Array2BIO: from microarray expression data to functional annotation of co-regulated genes
Background: There are several isolated tools for partial analysis of microarray expression data. To provide an integrative, easy-to-use and automated toolkit for the analysis of A...
Gabriela G. Loots, Patrick S. G. Chain, Shalini Ma...
BMCBI
2006
103views more  BMCBI 2006»
13 years 7 months ago
Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
Sébastien Lemieux
BMCBI
2005
121views more  BMCBI 2005»
13 years 6 months ago
Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data
Background: A critical step in processing oligonucleotide microarray data is combining the information in multiple probes to produce a single number that best captures the express...
Kerby Shedden, Wei Chen, Rork Kuick, Debashis Ghos...
BMCBI
2007
179views more  BMCBI 2007»
13 years 7 months ago
Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data
Background: The wide use of Affymetrix microarray in broadened fields of biological research has made the probeset annotation an important issue. Standard Affymetrix probeset anno...
Hui Yu, Feng Wang, Kang Tu, Lu Xie, Yuan-Yuan Li, ...