The identification of genes that influence the risk of common, complex diseases primarily through interactions with other genes and environmental factors remains a statistical and ...
Marylyn D. Ritchie, Christopher S. Coffey, Jason H...
Background: Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing...
Su Yeon Kim, Kirk E. Lohmueller, Anders Albrechtse...
In general frequent itemsets are generated from large data sets by applying association rule mining algorithms like Apriori, Partition, Pincer-Search, Incremental, Border algorithm...
Background: Genomewide association studies have resulted in a great many genomic regions that are likely to harbor disease genes. Thorough interrogation of these specific regions ...
Ryan Abo, Jathine Wong, Alun Thomas, Nicola J. Cam...
Background: Risk for complex disease is thought to be controlled by multiple genetic risk factors, each with small individual effects. Meta-analyses of several independent studies...