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BMCBI
2010
84views more  BMCBI 2010»
13 years 7 months ago
A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis
Background: The success achieved by genome-wide association (GWA) studies in the identification of candidate loci for complex diseases has been accompanied by an inability to expl...
Benjamin A. Logsdon, Gabriel E. Hoffman, Jason G. ...
BMCBI
2006
116views more  BMCBI 2006»
13 years 7 months ago
A model-based approach to selection of tag SNPs
Background: Single Nucleotide Polymorphisms (SNPs) are the most common type of polymorphisms found in the human genome. Effective genetic association studies require the identific...
Pierre Nicolas, Fengzhu Sun, Lei M. Li
BMCBI
2004
112views more  BMCBI 2004»
13 years 7 months ago
MuTrack: a genome analysis system for large-scale mutagenesis in the mouse
Background: Modern biological research makes possible the comprehensive study and development of heritable mutations in the mouse model at high-throughput. Using techniques spanni...
Erich J. Baker, Leslie Galloway, Barbara Jackson, ...
ASSETS
2004
ACM
14 years 27 days ago
Text entry from power wheelchairs: edgewrite for joysticks and touchpads
Power wheelchair joysticks have been used to control a mouse cursor on desktop computers, but they offer no integrated text entry solution, confining users to point-and-click or p...
Jacob O. Wobbrock, Brad A. Myers, Htet Htet Aung, ...
GECCO
2010
Springer
191views Optimization» more  GECCO 2010»
14 years 7 days ago
Initialization parameter sweep in ATHENA: optimizing neural networks for detecting gene-gene interactions in the presence of sma
Recent advances in genotyping technology have led to the generation of an enormous quantity of genetic data. Traditional methods of statistical analysis have proved insufficient i...
Emily Rose Holzinger, Carrie C. Buchanan, Scott M....