Transcription factors play essential role in the gene regulation in higher organisms, binding to multiple target sequences and regulating multiple genes in a complex manner. In or...
Akinori Sarai, Samuel Selvaraj, M. Michael Gromiha...
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Background: A complete understanding of the regulatory mechanisms of gene expression is the next important issue of genomics. Many bioinformaticians have developed methods and alg...
Computationally identifying transcription factor binding sites in the promoter regions of genes is an important problem in computational biology and has been under intensive resea...
Background: Cis-regulatory modules (CRMs) are distinct, genomic regions surrounding the target gene that can independently activate the promoter to drive transcription. The activa...