We propose a compositional approach to the dynamics of gene regulatory networks based on the stochastic π-calculus, and develop a representation of gene network elements which can...
Boolean models of genetic regulatory networks (GRNs) have been shown to exhibit many of the characteristic dynamics of real GRNs, with gene expression patterns settling to point a...
We address the applicability of blind source separation (BSS) methods for the estimation of hidden influences in biological dynamic systems such as metabolic or gene regulatory net...
We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple orga...
Manuel Middendorf, Anshul Kundaje, Chris Wiggins, ...
Robust stability serves as an important regulation mechanism in system biology and synthetic biology. In this paper, the robust stability analysis problem is investigated for a cla...