Background: Structure identification of dynamic models for complex biological systems is the cornerstone of their reverse engineering. Biochemical Systems Theory (BST) offers a pa...
Marco Vilela, Carlos Cristiano H. Borges, Susana V...
Dendritic cells are antigen presenting cells that provide a vital link between the innate and adaptive immune system, providing the initial detection of pathogenic invaders. Resea...
Background: Modelling of time series data should not be an approximation of input data profiles, but rather be able to detect and evaluate dynamical changes in the time series dat...
Ryoko Morioka, Shigehiko Kanaya, Masami Y. Hirai, ...
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
The toxicity of an anticancer drug is cleared from the body by different processes, including saturable metabolic and nonsaturable renal-excretion pathways. According to the princ...