Background: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligan...
Nikolaos G. Sgourakis, Pantelis G. Bagos, Panagiot...
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
We present a general, simple feature representation of sequences that allows efficient inexact matching, comparison and classification of sequential data. This approach, recently ...
— A DNA sequence can be described as a string composed of four symbols: A, T, C and G. Each symbol represents a chemically distinct nucleotide molecule. Combinations of two nucle...
Background: G protein-coupled receptors (GPCRs) transduce a wide variety of extracellular signals to within the cell and therefore have a key role in regulating cell activity and ...
Catherine L. Worth, Annika Kreuchwig, Gunnar Klein...