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» Algorithms for optimizing production DNA sequencing
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BMCBI
2005
201views more  BMCBI 2005»
13 years 7 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
EMO
2006
Springer
117views Optimization» more  EMO 2006»
13 years 9 months ago
Multiplex PCR Assay Design by Hybrid Multiobjective Evolutionary Algorithm
Abstract. Multiplex Polymerase Chain Reaction (PCR) assay is to amplify multiple target DNAs simultaneously using different primer pairs for each target DNA. Recently, it is widely...
In-Hee Lee, Soo-Yong Shin, Byoung-Tak Zhang
WABI
2007
Springer
139views Bioinformatics» more  WABI 2007»
14 years 1 months ago
Computability of Models for Sequence Assembly
Graph-theoretic models have come to the forefront as some of the most powerful and practical methods for sequence assembly. Simultaneously, the computational hardness of the underl...
Paul Medvedev, Konstantinos Georgiou, Gene Myers, ...
BMCBI
2002
120views more  BMCBI 2002»
13 years 7 months ago
tacg - a grep for DNA
Background: Pattern matching is the core of bioinformatics; it is used in database searching, restriction enzyme mapping, and finding open reading frames. It is done repeatedly ov...
Harry Mangalam
GECCO
2004
Springer
137views Optimization» more  GECCO 2004»
14 years 26 days ago
Evolving Better Multiple Sequence Alignments
Aligning multiple DNA or protein sequences is a fundamental step in the analyses of phylogeny, homology and molecular structure. Heuristic algorithms are applied because optimal mu...
Luke Sheneman, James A. Foster