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» Alignment of Non-Overlapping Sequences
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BMCBI
2007
142views more  BMCBI 2007»
13 years 10 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...
BMCBI
2006
129views more  BMCBI 2006»
13 years 10 months ago
Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Rober...
BMCBI
2010
126views more  BMCBI 2010»
13 years 10 months ago
Cgaln: fast and space-efficient whole-genome alignment
Background: Whole-genome sequence alignment is an essential process for extracting valuable information about the functions, evolution, and peculiarities of genomes under investig...
Ryuichiro Nakato, Osamu Gotoh
BMCBI
2004
119views more  BMCBI 2004»
13 years 10 months ago
PASS2: an automated database of protein alignments organised as structural superfamilies
Background: The functional selection and three-dimensional structural constraints of proteins in nature often relates to the retention of significant sequence similarity between p...
Anirban Bhaduri, Ganesan Pugalenthi, Ramanathan So...
CSB
2004
IEEE
208views Bioinformatics» more  CSB 2004»
14 years 2 months ago
Pair Stochastic Tree Adjoining Grammars for Aligning and Predicting Pseudoknot RNA Structures
Motivation: Since the whole genome sequences for many species are currently available, computational predictions of RNA secondary structures and computational identifications of t...
Hiroshi Matsui, Kengo Sato, Yasubumi Sakakibara