Abstract. Accurate comparative analysis tools for low-homology proteins remains a difficult challenge in computational biology, especially sequence alignment and consensus folding ...
Abstract. Sequence alignment algorithms have a long standing tradition in bioinformatics. In this paper, we formulate an extension to existing local alignment algorithms: local ali...
Background: Currently available methods to predict splice sites are mainly based on the independent and progressive alignment of transcript data (mostly ESTs) to the genomic seque...
Sequence alignment visualization is an important tool for understanding genomics data. Current approaches have difficulty scaling to the larger data sets becoming available. In th...
Abstract. We present a method for using aligned ontologies to merge taxonomically organized data sets that have apparently compatible schemas, but potentially different semantics f...